Welcome at the E.R.D.E.-AAK-Diagnostik GmbH


E.R.D.E.-AAK-Diagnostik GmbH is a diagnostics laboratory that on a commercial base offers the detection of diverse autoantibodies (agAAB) in sera.


At present the following disease associated autoantibodies can be detected:

- Autoantibodies against the β1-adrenergic receptor

- Autoantibodies against the β2-adrenergic receptor

- Autoantibodies against the α1- adrenergic receptor

- Autoantibodies against the muscerinergic M2 receptor

- Autoantibodies against the Angiotensin II Type1-receptor

- Autoantibodies against the Endothelin-receptor

- Autoantibodies against the PAR-receptor


The agAAB status of the following disease associated autoantibodies can be analysed:

- DCM, Myocarditis ( β1- & M2-AAB )

- Hypertension ( α1- & AT1- & ET-AAB )

- Diabetes type 2 ( α1- & AT1 & ET-AAB )

- Dementia ( α1- & β2-AAB )

- Allograft Rejection ( α1- & AT1-AAB )

- Dialysis associated Diseases ( α1- & AT1-AAB )

- Glaucoma ( β2-AAB )

- TAO, Thrombangitis obliterans - Buergers's Disease ( α1- & ET- & PAR-AAB )

- POTS (pdf), Posturales orthostatic tachycardia syndrom ( α1- & AT1- & β1- & β2- & M2- & ET- AAB )


The detection of the agonistic Autoantbodies (agAAB) is realized by the following analysis techniques:

- ELISA (not functional): Detection of a single agAAB

- BIOASSAY (functional): Analysis of all agAAB of the sample

- CALCIUM (functional): Measurement of intracellular calcium transients

 

Issued Patents (E.R.D.E.-AAK-Diagnostik GmbH)

1.EU-Patent: Bimmler et al. 02.08.2017 (Patent No.: EP 2 742 065 B1)

2.US-Patent: Bimmler et al., Jul.18, 2017 (Patent No.: US 9,708,372 B2)

 

Results on clinical Relevance of the Immunoadsorptions of Agonistic Antibodies Against α1-Adreneric Receptors in Patients with Mild to Moderate Dementia (Frontiers in Bioscience 2018, Content of Frontiers in Bioscience 2018, Therapeutic Apheresis and Dialysis 2016).

 

DATA PROTECTION

From 25.5.2018 the new General Data Protection Regulation of the European Union (DSGVO) will apply. The necessary informationen from the ERDE-AAK-Diagnostik GmbHcan found here.